Busting Biofilms With Saccharomyces Boulardii

Keeping your gut microbiome in balance is essential for maintaining good health. Unfortunately, bad bacteria can accumulate in the digestive tract and cause a number of unpleasant symptoms—enter Saccharomyces boulardii to save the day! This remarkable organism has the unique ability to balance out the good and bad bacteria in your gut, helping to get rid of bad bacteria by busting biofilms, eradicating yeast overgrowth, and promoting a healthy microbiome.

Do you ever wonder how your gut stays in balance? How can it detect the difference between good and bad bacteria, and keep an optimally balanced microbiome? Well, it turns out that Saccharomyces boulardii plays a big role in this process.

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What is Saccharomyces boulardii?

S. boulardii is a powerful probiotic yeast that helps to promote a healthy balance of gut bacteria. When taken in supplement form, it can help to protect good gut bacteria, while fending off harmful pathogens to improve overall digestion.

S. Boulardii for overall gut health

S. Boulardii supports a healthy gut, and may protect against harmful pathogens, including bacteria, viruses, and fungi that can cause unpleasant digestive symptoms. It has been shown effective against the following bacteria and GI problems, but new research is always evolving (1):

  • Antibiotic-associated diarrhea
  • C. difficile (C. diff), E. coli, and H. pylori infections
  • Acute gastroenteritis
  • IBD & IBS

Saccharomyces boulardii has anti-microbial and anti-inflammatory properties that benefit gut health and help to promote healthy, normal digestion. You can find Saccharomyces boulardii in Belly Fix as part of a carefully formulated digestive blend.

Busting biofilms with S. boulardii

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One of the unique benefits of Saccharomyces boulardii is its ability to bust through biofilms. Biofilms are protective coatings that harmful bacteria create to protect themselves from antibiotics and your immune system (2). Saccharomyces boulardii has the ability to penetrate these biofilms, allowing the immune system and other antimicrobial agents to more effectively fight off the harmful bacteria.

This makes it an effective tool in combating bacterial infections and preventing the recurrence of infections caused by biofilm-forming bacteria.

Related: Do You Have SIBO?

Eradicating yeast overgrowth

Another remarkable benefit of Saccharomyces boulardii is its ability to combat yeast overgrowth, specifically an overgrowth of Candida albicans. Candida overgrowth can lead to a variety of symptoms including bloating, gas, and fatigue, and can be difficult to treat. However, studies have shown that Saccharomyces boulardii can help to reduce the growth of Candida, leading to improvements in symptoms and a healthier gut (3).  

Saccharomyces boulardii to manage inflammatory digestive conditions

In addition to combating bacterial infections and eradicating yeast overgrowth, Saccharomyces boulardii has been found to have anti-inflammatory properties that benefit inflammatory digestive conditions like inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). These conditions can cause significant discomfort and disrupt normal daily activities, but studies have shown that Saccharomyces boulardii helps to reduce inflammation in the gut, leading to improvements in symptoms and better overall gut health (4).

Listen: How to Eat for Your Inflammation Type with Maggie Berghoff

S. boulardii can withstand the harsh environment of the stomach

S. boulardii has been shown to survive the harsh digestive environment that can kill other probiotic bacteria. In order for probiotics to be effective, they have to live long enough to make it to the part of the digestive system they colonize—usually the large intestine. Most probiotics lose much of their effectiveness by the time they reach the colon.

S. boulardii was able to survive after being in an acidic environment (like in the stomach) and exposure to enzymes and bile salts. In comparison, normal probiotic bacteria are usually “severely impaired” after exposure to an intestinal environment (1).

Read: How to Choose a Probiotic for Hormone Balance, Weight Loss, Mood, & More

S. boulardii protects the gut after an antibiotic

Antibiotics are often a necessary and sometimes life-saving medicine, but they can also have unintended consequences for your microbiome, wiping out both good and bad bacteria in the process of treating an infection. A course of antibiotics can then hinder the protective role of the gut microbiome, making you susceptible to harmful overgrowth from opportunistic “bad” bacteria until your healthy microbiome is re-established—which can take several weeks.

S. boulardii helps to restore the normal microbiome balance after taking an antibiotic, even though it doesn’t directly colonize the gut itself. It can help modulate the microbiome and decrease the likelihood that bad bacteria will take over (1).

May protect against infectious bacteria

S. boulardii has antimicrobial activity that can prevent harmful pathogens from growing in the digestive system. It may limit the growth of pathogenic bacteria including E. coli and C. difficile, which are two common causes of antibiotic-associated diarrhea and colitis (1).

How to take S. boulardii

S. boulardii is available in supplement form—usually capsules or a powder. The recommended dosage varies, so it is best to follow the instructions on the packaging or consult with a holistic healthcare professional.

Belly Fix contains Saccharomyces boulardii as an important part of an overall protocol to heal the gut and restore balance to the microbiome. A balanced microbiome is a foundational part of every aspect of health, including hormone balance, a healthy weight, and even mental and emotional health.

What to remember

Saccharomyces boulardii is a special probiotic yeast that can help to promote a healthy microbiome, bust through biofilms, eradicate yeast overgrowth, and protect against harmful pathogens. Its ability to survive in harsh digestive conditions makes it an effective probiotic supplement for many people. 

Overall, Saccharomyces boulardii is a powerful tool for promoting gut health and balance. Whether you’re dealing with chronic gut issues, or just looking to maintain a healthy digestive system, incorporating this probiotic yeast into your routine can lead to significant improvements


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344949/
  2. https://kids.frontiersin.org/articles/10.3389/frym.2022.626305
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7711718/
  4. https://pubmed.ncbi.nlm.nih.gov/31923554/
Dr. Taz Bhatia M.D.